The A35 was closed between Dorchester and Bridport after a lorry overturned in a crash.
Police said it happened near Winterbourne Abbas earlier this morning.
The road was closed between Monkeys Jump roundabout, Dorchester and Sea Road South (Mitsubishi) roundabout in Bridport.
No time frame was given for how long the road might be closed for due to the 'complexity of the recovery work needed', according to Travel Dorset.
A Dorset Police spokesman said earlier: "Officers are at the scene and we would like to thank members of the public for their patience and understanding while the closures are in place."
The road has now reopened. Read our story here
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